If you're looking to set up your 12 gauge shotgun for defensive use, do yourself a favor and use a dedicated tactical load like this one from NobelSport.
These 2-3/4" shells are loaded a bit less "hot" than hunting ammo; they retain more than enough power to stop an assailant, but produce more controllable recoil for faster aimed fire. In addition, they are less likely to overpenetration and cause collateral damage.
Each shell in this box of 10 fires 9 pellets of 00 buckshot at a muzzle velocity of 1,200 feet per second.
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